Pathology Microscopy Solutions for Tissue Review and Research

A microscopy lab test uses a microscope to examine cells, tissues, microorganisms, or material samples at magnification. In pathology, microscopy commonly supports review of stained tissue sections to assess cellular structure and identify areas requiring closer evaluation. The microscope itself does not replace clinical interpretation; qualified laboratory and pathology professionals evaluate findings within established diagnostic and laboratory procedures.

Histopathology commonly uses a brightfield microscope to examine stained sections, especially H&E slides. Laboratories may also use digital microscopes such as SeBa2 and SeBaPro4, fluorescence microscopes such as SLi3Pro and SLi6Pro, or the Accuva Cellect laser capture microdissection system, depending on the goal.

Laser capture microdissection lets a user select cells or regions under a microscope and isolate them for downstream analysis. Accuva Cellect uses an infrared laser for single cells or small groups and a UV laser for dense structures. This reduces background from surrounding tissue and keeps a link to morphology.

AI-assisted pathology image analysis applies trained deep-learning models to segmentation and quantification. It can standardize repetitive steps and reduce variation between users, but results need workflow validation and expert oversight. LEAP AI pairs Accuva LEAP optics with Media Cybernetics Image-Pro AI.

Yes. Laxco lists FFPE and fresh-frozen tissue, H&E-stained and LCM-optimized stained sections, immunofluorescence, unstained samples, and cell culture for Accuva Cellect. Consider fixation history, stain, and downstream assay requirements when setting up an FFPE workflow.

A strong pathology imaging workflow typically includes suitable optics, reliable image capture, clear slide and sample handling procedures, analysis tools, data storage, and reporting capabilities. For molecular applications, it may also include laser capture microdissection, extraction methods, amplification, and sequencing preparation. Integrating these stages helps teams reduce handoffs, improve traceability, and maintain a consistent path from visual review to results.

Yes. Laser capture microdissection lets researchers isolate morphologically defined cells or regions while documenting their location. The captured material can be used in region-specific RNA, DNA, or protein workflows, which can reveal differences that whole-section extraction averages out.

Laxco provides application training, technical support, and documentation such as manuals, brochures, application notes, and videos. For Accuva Cellect, it offers on-site and virtual training, a 48-hour response commitment, and Grant Language Kits for research proposals.