MS Sample Preparation
Isolate defined cells or regions for protein extraction, giving mass spectrometry an input that reflects the target population.
Mass spectrometry-based proteomics of single cells and small populations depends on collecting the intended cells with minimal surrounding tissue. Laxco's Accuva Cellect laser capture microdissection system isolates selected cells or regions from tissue sections, giving proteomic workflows a compositionally defined input.
Cell isolation for mass spectrometry-based proteomic workflows.
Isolate defined cells or regions for protein extraction, giving mass spectrometry an input that reflects the target population.
The infrared laser captures single cells or small groups for low-input proteomic workflows.
Profile defined tissue regions by mass spectrometry and compare compartments that a bulk lysate would average together.
Cell-type-specific starting material reduces dilution by adjacent tissue in biomarker research.
Collect scarce or scattered cells individually to concentrate material for proteomic analysis.
Use the infrared laser for single cells and the UV laser for larger or denser regions, depending on the sample.
Using the five-step software workflow with visual quality control, researchers review stained or unstained sections and identify the cells or regions relevant to their proteomic question.
Cell isolation technology and application support for proteomics research.
Accuva Cellect is ETL certified by Intertek for compliance with applicable UL/CSA safety standards in North America.
Grant Language Kits help researchers describe LCM in NIH, NSF, HHMI, and DOD proposals.
LEAP AI combines Accuva LEAP optics with deep-learning segmentation to apply consistent analysis across images.
On-site and virtual application training, live technical support, and a 48-hour response commitment, from installation to workflow questions.
The team behind Laxco's laser capture microdissection technology.
Laxco, Inc. is a provider of optical and measurement technologies headquartered in Mill Creek, Washington, with more than 20 years in precision optics and microscopy. Its Accuva Cellect laser capture microdissection system supports researchers who isolate defined cells for proteomic and genomic analysis. Through its partnership with Media Cybernetics, Laxco offers LEAP AI, which pairs Accuva LEAP optics with deep-learning image analysis. Laxco also provides application training, live technical support, and Grant Language Kits for research proposals.
Plan the number of cells or tissue area needed per sample, the staining method, protein extraction chemistry, and mass spectrometer access. Costs depend mainly on sample numbers and instrument time, so run a pilot to set inputs before budgeting a full study.
Talk to a Laxco specialist about isolating cells for your mass spectrometry proteomics workflow.
Grant Language Kits and a Grant Fit consultation for NIH, NSF, HHMI, and DOD proposals.
LEAP AI pairs Accuva LEAP optics with Media Cybernetics Image-Pro AI.
Share your research goals and a Laxco specialist will help you plan cell isolation and sample preparation for your mass spectrometry workflow.
For immediate assistance, feel free to give us a direct call at 425-686-3081. You can also send us a quick email at info@laxcoinc.com.
For immediate assistance, feel free to give us a direct call at 425-686-3081. You can also send us a quick email at info@laxcoinc.com.